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BioProcess Simulator · S. cerevisiae
KJBBIOPROCESS SIMULATION LAB

BioProcess Simulator MODEL

S. cerevisiae
ReadyEthanol production by Saccharomyces cerevisiae
20.0

15.0

10.0

5.0

0.0
O20.0 %CO20.0 % pO2100.0 %pH7.1 TR20.0 °CVolume0.0 LFoam0.0 L
Antifoam◇1.40 L0.00 ml/min
Base◇1.40 L0.00 ml/min
Acid◇1.40 L0.00 ml/min
ProductLevel  0.0 L
Thermal fluid20.0 °C
μ 0.000 h⁻¹X 0.00 g/LS 0.00 g/LP 0.00 g/LD 0.000 h⁻¹
System ready. Start a new process.Model readySamples: 0
Data:
Trends:
Measurements:

© 2026 Katharina Julia Brenner

PROCESS MODULE · GM-03

Gas mixing station

Three independent mass-flow channels for oxygen control and anaerobic operation.

01
OxygenO2 · 0-20 L/min
0.0 L/min
02
Process airAir · 0-60 L/min
0.0 L/min
03
NitrogenN2 · 0-20 L/min
0.0 L/min

Auto follows the pO2 strategy. Manual unlocks the flow slider. Off closes the channel.

Medium preparation

Configure initial substrate concentration and working volume.

Bioprocess model setup

Choose the operating mode, oxygen environment and kinetic parameters.

Monod kinetics
Stoichiometry
Flow strategyContinuous mode regulates the outflow around the volume setpoint. Batch disables all feed.
μ = μmax · S/(Ks + S) · fO2d(XV)/dt = μXV − FoutXd(SV)/dt = FinSin − FoutS − qSXV

Controller

Setpoints, gain and integral time directly affect the automatic loops.

Dissolved oxygen
pH
Temperature
Level
Antifoam
LIVE INSTRUMENT PANEL · PI-06

Process data

Current online measurements and automatically stored sample results.

Online measurements

Live signal
T mediumTemperature
453015
20.0 °C20.0 °C
V mediumReactor volume
20100
0.0 L0.0 L
pHAcidity
975
7.17.1
pO2Dissolved oxygen
100500
100.0 %100.0 %
O2Off-gas oxygen
1260
0.0 %0.0 %
CO2Off-gas carbon dioxide
1890
0.0 %0.0 %

Last sample

Stored locally
Biomass total n/aBiomass viable n/aSubstrate I n/aSubstrate II n/aProduct n/a

Samples are stored automatically in this browser.

No.Process timeModeX totalS IProduct
No samples recorded yet.
CULTIVATION HISTORY · HI-01

Online trends

Live measurements for observing and evaluating the cultivation.

Recording1 data pointWindow 00:00:00